Genomics & regulation
Study chromatin accessibility and regulatory changes from compatible bulk or single-cell assays.
Analyses are tailored to your experimental design, data quality and research question. The workflow and deliverables are agreed following project review.
Analysis modules
Assay-specific QC and peak or region quantification.
Differential accessibility or binding.
Peak annotation and region-to-gene context.
Transcription-factor motif enrichment.
Single-cell chromatin clustering and reference integration.
RNA–chromatin associations and multimodal analysis.
DNA methylation comparisons as a separate assay-specific workflow.
Data and metadata
ATAC-seq, ChIP-seq, CUT&Tag or methylation-derived data; aligned files, peaks or count matrices as appropriate; controls and reference genome.
Proposed deliverables
Annotated regulatory regions; differential results; genomic coverage figures; motif and integration summaries.
Interpretation and feasibility
Different assays require distinct processing and controls. Motif enrichment and correlated peak–gene links are not proof of physical binding or causal regulation.
Methods and references
Methods, reference resources and software are selected for each project after protocol, feasibility and licence review. Applicable versions, references and interpretation limits are documented in the agreed workflow.