Molecular & integrative analysis

Pathway, Signature & Network Analysis

Pathway, Signature & Network Analysis

Place molecular changes into gene sets, pathways and interpretable biological networks.

Illustrative schematic — not experimental data

Analyses are tailored to your experimental design, data quality and research question. The workflow and deliverables are agreed following project review.

Analysis modules

Gene identifier harmonization and background-universe review.

Over-representation analysis.

Ranked gene-set enrichment.

Sample-level pathway and signature scoring.

Comparisons of enriched programs across contrasts.

Exploratory transcription-factor activity and network context.

Data and metadata

Gene lists with the tested universe; ranked statistics; or compatible expression matrices, depending on the analysis. Organism and identifier system are required.

Proposed deliverables

Annotated enrichment tables; leading-edge genes where relevant; pathway figures and background/collection/version documentation.

Interpretation and feasibility

Statistical enrichment is not causal pathway activation. Gene-set and database licences are separate from the analysis package licence.

Methods and references

Methods, reference resources and software are selected for each project after protocol, feasibility and licence review. Applicable versions, references and interpretation limits are documented in the agreed workflow.